Located in the heart of Southern Illinois, Williamson County Regional Airport is the region's sole primary commercial service airport providing daily flights to St. Louis on Great Lakes Airlines.

Other services include car rentals, restaurant, hotel, air cargo, and a Fixed Base Operator providing flight instruction, charter, aircraft rental, maintenance, and fueling. 

Combined with other businesses located on the airport, the facility generates an annual economic impact of over $10 million to the area.